Small joints, outsized consequences — thumb base arthritis affects nearly everything you do with your hands.
The carpometacarpal joint at the thumb base is a saddle joint built for an unusual range of motion, and that mobility comes at the cost of stability. It bears substantial load — pinch force at the tip translates to many times that at the joint — which is why it wears out so commonly and why arthritis there affects nearly every task involving your hands.
Small joint evidence is more limited than for the knee or elbow. Studies on thumb CMC arthritis are smaller and fewer, though the early results are reasonably encouraging, with some trials suggesting benefit over corticosteroid at longer follow-up.
We would characterise this as promising rather than established, and we will say so rather than present it as settled.
Small joints hold very little volume — a thumb CMC joint accepts only a fraction of what a knee does. Accurate placement therefore matters enormously, and the injection is more technically demanding than a large joint. It is also more uncomfortable, because there is little soft tissue to buffer the injection.
For thumb base arthritis, a well-fitted CMC orthosis has good supporting evidence and is worth doing regardless of whether you have an injection. Hand therapy focusing on the thenar muscles and joint protection strategies — changing how you grip, using adapted tools — makes a real difference to daily function.
For trigger finger, PRP is not the appropriate treatment. That is a mechanical problem where the tendon cannot glide through a thickened pulley, and it responds to steroid injection or a straightforward surgical release.
Dr. Daniel Moghadam performs these injections himself. Accurate placement matters enormously with joint and tendon injections — product delivered into the wrong plane does nothing useful — and the assessment of whether PRP suits your problem at all is a clinical judgement rather than a checklist.
PRP's evidence base varies considerably by indication. Some uses are well supported by controlled trials; others are promising but thin. We will tell you which category yours falls into rather than presenting all applications as equally proven.
For most musculoskeletal problems, progressive loading and rehabilitation remain the foundation of treatment. PRP can support that process; it rarely replaces it. If you have not done structured rehabilitation, that is usually the first conversation.
PRP does not repair a complete tendon rupture, reverse advanced bone-on-bone arthritis, or fix mechanical instability. Where a surgical opinion is the honest recommendation, that is what you will hear.
Dr. Moghadam examines the joint, reviews any imaging you have, and determines whether PRP is genuinely likely to help your specific problem — or whether something else is the better answer.
A small volume of your blood is drawn, comparable to a routine laboratory test.
The sample is spun to concentrate the platelets and separate them from red blood cells. This takes ten to fifteen minutes.
The concentrate is injected into the target tissue. Local anesthetic is used, though not always inside the joint itself, since it can affect platelet function.
Relative rest for the first few days, then a graded return to activity. Improvement typically builds over four to twelve weeks.
The evidence is more limited than for larger joints — studies are smaller and fewer — but early results are reasonably encouraging, with some trials suggesting benefit over corticosteroid at longer follow-up. We would describe it as promising rather than established, and we would rather say that plainly.
The carpometacarpal joint is a saddle joint built for exceptional mobility, and that comes at the cost of stability. It also bears disproportionate load — pinch force at the fingertip translates to many times that at the joint. That combination is why it wears out so commonly, particularly in women over 50.
Yes — a well-fitted CMC orthosis has good supporting evidence for thumb base arthritis and is worth using regardless of whether you have an injection. It works by limiting the movement that aggravates the joint during loaded tasks. Hand therapy for the thenar muscles and joint protection strategies also make a genuine difference.
Generally yes. There is little soft tissue to buffer the injection and the joint holds very little volume, so the pressure is more noticeable. It is brief, and we use local anesthetic, but we would not describe small joint injections as comfortable.
No, and this is a case where we would steer you elsewhere. Trigger finger is a mechanical problem — the tendon cannot glide smoothly through a thickened pulley. It responds well to corticosteroid injection or a simple surgical release. PRP does not address the mechanical obstruction.
That is inflammation of the tendon sheath on the thumb side of the wrist, and it typically responds well to a corticosteroid injection combined with splinting and activity modification. PRP is not the first-line treatment for it.
You should avoid heavy gripping and pinching for several days. Most patients manage normal light daily activity within a day or two, but plan around anything requiring forceful hand use. Improvement builds over six to twelve weeks.
For advanced thumb base arthritis with significant deformity and joint destruction, surgical options such as trapeziectomy have well-established outcomes. If your joint has reached that stage, an injection is unlikely to give you what you want and a hand surgery opinion is the honest recommendation.
Patients travel to our Beverly Hills office for wrist & finger pain treatment from across Los Angeles:
Our Beverly Hills office sits on Wilshire Blvd near the Beverly Hills–Los Angeles border, with on-site, valet, and street parking.
8907 Wilshire Blvd, Suite 270
Beverly Hills, CA 90211
Mon–Thu 10am–5pm
Fri 9am–5pm
Sat & Sun Closed
Thumb and wrist pain affects almost everything. A consultation will establish what is causing yours and what genuinely helps.